HYPOGLYCEMIA

HypoglycemiaʻO ia ke kumu palena nui i ka hoʻokele glycemic o ka maʻi diabetes type 1.Hoʻokaʻawale ʻia ʻo Hypoglycemia i ʻekolu mau pae:
• Ua pili ka Papa 1 i ka waiwai glucose ma lalo o 3.9 mmol/L (70 mg/dL) a oi aku a i ole like me 3.0 mmol/L (54 mg/dL) a ua kapaia ma ke ano he waiwai makaala.
• Papa 2 nokoko kokoAia nā waiwai ma lalo o 3.0 mmol/L (54 mg/dL) a manaʻo ʻia he hypoglycemia koʻikoʻi.
• Hoʻonohonoho ka Papa 3 i kekahi hypoglycemia i hōʻike ʻia e ke kūlana noʻonoʻo a/a i ʻole ke kūlana kino e pono ai ke komo ʻana o kekahi ʻaoʻao no ka hoʻōla.
ʻOiai ua hoʻomohala mua ʻia kēia mau mea no ka hōʻike ʻana i nā hoʻokolohua lapaʻau, he mau hale lapaʻau kūpono lākou.Pono e nānā pono i ka pale ʻana i ka pae 2 a me 3 hypoglycemia.
He mea maʻamau ka hypoglycemia pae 1, me ka hapa nui o ka poʻe me ka maʻi maʻi type 1 e ʻike nei i kekahi mau manawa i kēlā me kēia pule.ʻO ka Hypoglycemia me nā pae glucose ma lalo o 3.0 mmol/L (54 mg/dL) ʻoi aku ka nui o nā manawa ma mua o ka mahalo ʻia.ʻAʻole maʻamau ka pae 3 hypoglycemia akā ua loaʻa i ka 12% o nā pākeke me ka maʻi maʻi type 1 ma kahi o 6 mau mahina ma kahi loiloi nānā honua.Ua hōʻike ʻia kekahi mau haʻawina ʻaʻole i emi ka nui o ka hypoglycemia, ʻoiai me ka hoʻohana nui ʻana o ka insulin analogs a me CGM, aʻo nā haʻawina ʻē aʻe i hōʻike i ka pōmaikaʻi me kēia mau holomua therapeutic.

ʻO nā pilikia no ka hypoglycemia, ʻoi aku ka pae 3 hypoglycemia, ʻo ia ka lōʻihi o ka maʻi diabetes, ka makahiki ʻelemakule, ka mōʻaukala o ka hypoglycemia pae 3 hou loa, ka inu ʻana i ka waiʻona, hoʻoikaika kino, haʻahaʻa haʻahaʻa haʻahaʻa, haʻahaʻa haʻahaʻa o ka loaʻa kālā o ka home, ka maʻi maʻi maʻi maʻi, a me IAH.ʻO nā kūlana endocrine, e like me ka hypothyroidism, adrenal a me ka ulu ʻana o ka hormone deficiency, a me ka maʻi celiac hiki ke hoʻonui i ka hypoglycemia.Hoʻopaʻa mau ʻia nā ʻikepili maʻi diabetes kahiko i ka poʻe me nā pae haʻahaʻa HbA 1c he 2-3-paila kiʻekiʻe o ka pae 3 hypoglycemia.Eia naʻe, i ka ʻano 1DiabetesExchange Clinic Registry, ua hoʻonui ʻia ka pilikia o ka pae 3 hypoglycemia ʻaʻole wale i ka poʻe nona ka HbA 1c ma lalo o 7.0% (53 mmol/mol), akā pū kekahi me ka HbA 1c ma luna o 7.5% (58 mmol/mol).
Hiki ke wehewehe ʻia ka nele o ka pilina ma waena o HbA 1c a me ka pae 3 hypoglycemia ma ka hoʻonohonoho honua maoli e ka hoʻomaha ʻana o nā pahuhopu glycemic e ka poʻe me ka mōʻaukala o ka hypoglycemia, a i ʻole nā ​​mea hoʻohilahila, e like me ka lawa ʻole o nā ʻano hoʻokele ponoʻī e kōkua i nā mea ʻelua.hyper- a me hypoglyc-cemia.ʻO kahi kānana lua o ka hoʻokolohua IN CONTROL, kahi i hōʻike ʻia ai ka hōʻemi ʻana i ka pae 3 hypoglycemia i ka poʻe e hoʻohana ana i ka CGM, hōʻike i ka piʻi ʻana o ka pae o ka hypoglycemia pae 3 me ka HbA 1c haʻahaʻa, e like me ka mea i hōʻike ʻia ma ka DCCT.Hōʻike kēia i ka hoʻohaʻahaʻa ʻana i ka HbA 1c hiki ke hele mai me ka piʻi kiʻekiʻe o ka pae 3 hypoglycemia.
Ka make maihypoglycemiai ka maʻi diabetes type 1 ʻaʻole ia he mea liʻiliʻi.Ua ʻike ʻia kahi hoʻāʻo hou ma mua o 8% o nā make no ka poʻe ʻōpio ma mua o 56 mau makahiki mai ka hypoglycemia.He paʻakikī ke ʻano o kēia, me ka arrhythmias cardiac, ka hoʻoulu ʻana o ka ʻōnaehana coagulation a me ka mumū, a me ka endothelial dysfunction.ʻO ka mea i ʻike ʻole ʻia ʻo ia ka pae 3 hypoglycemia pili pū me nā hanana microvascular nui, ka maʻi nocardiovascular, a me ka make mai kekahi kumu, ʻoiai ʻo ka hapa nui o kēia mau hōʻike i loaʻa mai ka poʻe me ka maʻi diabetes type 2.E pili ana i ka hana cognitive, ma ke aʻo ʻana o DCCT a me EDIC, ma hope o 18 mau makahiki o ka hahai ʻana, ʻaʻole i ʻike ʻia ka hypoglycemia koʻikoʻi ma waena o nā pākeke waena i ka hana neu-rocognitive.Eia nō naʻe, kūʻokoʻa i nā mea pilikia ʻē aʻe a me nā comorbidities, ʻoi aku ka nui o nā manawa o ka hypoglycemia koʻikoʻi i hui pū ʻia me ka hoʻohaʻahaʻa nui ʻana i ka psychomotor a me ka hana noʻonoʻo i ʻike nui ʻia ma hope o 32 mau makahiki o ka hahai ʻana.ʻIke ʻia ʻoi aku ka maʻalahi o ka poʻe ʻelemakule me ka maʻi maʻi type 1 i ka pōʻino o ka naʻau e pili ana me ka hypoglycemia, ʻoiai ʻoi aku ka ulu ʻana o ka hypoglycemia i ka poʻe me ke kino naʻau.ʻAʻole i loaʻa ka ʻikepili CGM i ka wā DCCT a no laila ʻaʻole ʻike ʻia ka nui maoli o ka hypoglycemia koʻikoʻi i ka manawa.
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